Daily comfort starts with a compound your body already makes. 1200 mg of micronized PEA plus co-micronized luteolin to support everyday comfort.†
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Try it for 30 days from delivery. If it's not for you, we refund the product price. Keep the bottle. No questions asked.
“Life changing for my fibro. I’ve tried every supplement on Amazon and every prescription my doctor suggested. This is the first thing that’s actually worked. Sleep improved first, then the pain started dropping. Two months in and I feel like a different person.”
Patty M., USA · Verified Purchase ★★★★★
Blissta® PainBloc, proprietary PEA + Luteolin formula. Micronized Palmitoylethanolamide at 1200mg, co-micronized with 120mg luteolin. PEA is a natural fatty acid compound your body already produces, your built-in defense against pain and inflammation. After 45, your body stops making enough. Luteolin works alongside it to push the effect deeper and make it last longer.
What makes ours different: most PEA products stop at PEA. Ours co-micronizes both compounds together for 3x absorption. Manufactured in a GMP-certified facility. Every batch third-party tested with a publicly available Certificate of Analysis.
PEA activates PPAR-alpha receptors inside your cells, the master switches that control inflammation at the genetic level. Luteolin amplifies the effect by calming the same overactive cells from a second angle. Unlike CBD (works outside the cell) or gabapentin (blocks signals), this blend goes inside the cell to address the root cause.
1 · Calms mast cells. PEA and luteolin together tell overactive immune cells to stand down. Quiets the inflammation flood.
2 · Quiets glial cells. Restores normal nerve signal filtering. Stops pain amplification.
3 · Activates PPAR-alpha. Nuclear receptors that control inflammation at the gene level.
4 · Restores the system. Pain decreases, sleep improves, mood stabilizes, all at once.
Dosing: Loading phase (days 1 to 30): 2 capsules daily · Maintenance (day 31+): 1 capsule daily
† These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Per serving (2 capsules):
Micronized Palmitoylethanolamide (PEA), 1200mg: Clinical trial dose. 3x absorption vs standard PEA.
Co-Micronized Luteolin, 120mg: Works alongside PEA to deepen and extend the effect. The reason ours outperforms plain PEA.
What’s not in it: no fillers, no magnesium stearate, no rice flour, no maltodextrin, no artificial colors, no GMOs, gluten or soy.
Tested for: 99%+ purity verified, heavy metal free, micronized particle size, GMP-certified facility.
Why co-micronized matters: standard PEA has poor absorption, most passes through. Co-micronizing PEA with luteolin reduces particle size so your body can use both, and the two compounds reinforce each other. Every clinical trial showing results used micronized PEA.
Shipping. Ships within 24 hours Mon to Fri. Orders before 2 PM ET ship same day. Standard delivery 3 to 5 business days. Expedited options at checkout. Tracking emailed within 24 hours of dispatch.
30-Day Money-Back Guarantee. Try it for 30 days from delivery. If it’s not for you, email Riley at hello@blissta.co with your order number and we refund the product price within 24 hours. No questions asked. No return required. Keep the bottle.
25,000+ customers. Real people. Real pain relief.
"12 years of fibromyalgia. Tried gabapentin (zombie), Lyrica (40 pounds), CBD (placebo). My doctor was out of ideas. Found PEA through my own research. Sleep improved by week 2. By week 6, pain dropped noticeably. Three months in — cut my gabapentin in half with doctor guidance. This should have been offered to me a decade ago."
"20+ years of chronic pain and $30,000 wasted on supplements. Expected nothing. Sleep came first — around day 10 I stopped waking at 2am. By week 5 I was reaching for ibuprofen less. By month 2, I got on the floor to play with my granddaughter and got back up without help. I cried — from relief that something finally worked."
"Works. Not overnight — took a solid 3-4 weeks. But once it kicked in, the difference was undeniable. I ran the 'pause test' — skipped it for 4 days and the pain came roaring back within 48 hours. Restarted immediately. Now I'm subscribed. Only complaint: wish I'd found this 5 years ago instead of wasting money on CBD and Amazon supplements that did nothing."
"Nerve pain in both feet from diabetes. Nothing touched it — not gabapentin, not lidocaine patches, not the TENS unit. Shower water felt like fire. Started PainBloc at loading dose. By week 3, showers weren't torture anymore. By month 2, I can walk my dog around the block again. My wife noticed before I did — said I stopped wincing getting out of bed."
Your body makes its own comfort compound. It's called PEA. With age and everyday wear, your levels may not keep up with what your body needs.
Not another quick fix. Support for what your body already makes.
Try PainBloc Risk-FreePEA was first identified in the 1950s. Since then it has been studied by researchers around the world, including the lab of Nobel laureate Dr. Rita Levi-Montalcini.
*Research refers to PEA as an ingredient, not to PainBloc specifically. Full citations available on request.
PEA works by restoring your body's natural pain defense system, the one that broke down with age. It activates PPAR-alpha receptors inside your cells, calming the overactive mast cells and glial cells generating inflammation and amplifying pain signals.
Unlike painkillers that mask symptoms for hours, PEA rebuilds the system that was supposed to manage pain on its own. That's why it works better over time, not worse. And that's why it helps with pain, sleep, mood, and anxiety simultaneously, because mast cells and glial cells influence all of those systems.
Beyond pain, PEA has been studied for its neuroprotective properties, supporting healthy nerve function.
600+ scientific studies support the effectiveness of micronized Palmitoylethanolamide. Blissta PainBloc is formulated to restore your body's natural defense against pain and inflammation, nothing else added, nothing cut.
We use the exact form of PEA validated in clinical trials: micronized, at 1200mg, co-micronized with 120mg luteolin. Most PEA products stop at PEA. Ours doesn't. Every batch is manufactured in a GMP-certified facility under rigorous quality control.
Take it every day. Give it time to build. Then check in with how you feel.
4 capsules daily (2 morning, 2 evening, with food), 1200 mg total. PEA works best with steady daily use, so the only goal this month is not to miss a day.
Many people say the first thing they notice is how they sleep. Keep a simple note each morning of how you slept and how you feel.
Many people move to 2 capsules daily (600 mg). Around week 6 to 8, compare how you feel now to your notes from week one. That's your honest answer.
*Individual results vary. Always consult your healthcare provider before starting. Do not stop prescription medications without physician supervision.
The word on the front can match. What's inside, and how well your body can use it, often doesn't.
PEA has been used in Europe for 20+ years. Most Americans have never heard of it.
PainBloc is a dietary supplement, not a replacement for prescribed medication. Never stop or change a prescription without your doctor.
There are 200+ PEA products on Amazon. Most cut corners where it matters most: particle size, dose, sourcing. We built PainBloc on the opposite philosophy.
Micronized form. Clinical dose. GMP-certified manufacturing. Third-party tested with a public Certificate of Analysis, because if you can't verify what's in the bottle, you shouldn't be swallowing it.
Try it for 30 days from delivery. If it's not for you, email hello@blissta.co with your order number and we refund the product price within 24 hours. No questions. Keep the bottle.
Riley · Customer Care, Blissta
Straight answers. No hedge words. No fine print.
PEA (Palmitoylethanolamide) is a natural fatty acid compound your body already produces. Unlike CBD, which has 16 failed clinical trials for chronic pain (University of Bath, 2024), PEA has 11 successful randomized controlled trials across 774 patients. CBD works on receptors outside your cells. PEA activates PPAR-alpha receptors inside your cells.
Gabapentin and Lyrica numb pain signals, which is why they can cause brain fog, weight gain, and withdrawal. PEA calms the mast cells and glial cells generating inflammation and amplifying pain. It has a strong safety profile across 600+ studies. PainBloc is a supplement, not a replacement for any prescription.
Most users notice sleep improving within 2 to 3 weeks. Pain support typically builds over 4 to 8 weeks. Clinical studies showed a 35% reduction in month one and another 35% in month two. PEA builds over time.
Loading phase (first 30 days): 4 capsules daily, 2 morning and 2 evening, with food (1200mg total). Maintenance (day 31+): 2 capsules daily (600mg). This matches the clinical trial protocol that produced the strongest results.
PEA is generally well tolerated, but it can interact with some pain medications. If you take any prescription medication, check with your doctor or pharmacist before starting PainBloc.
Across 600+ clinical studies, no major adverse events have been attributed to PEA. No weight gain. No brain fog. No withdrawal. No tolerance buildup. One of the cleanest safety profiles of any pain-support compound studied.
PainBloc isn't a replacement for any prescription. Never stop or change gabapentin on your own. It needs slow, careful tapering under medical supervision, and stopping suddenly can cause serious withdrawal. Talk to your doctor about any change.
PEA is a fatty compound with poor water solubility. Standard PEA particles are too large for efficient absorption, so most passes through. Micronization reduces particle size so your body can actually use it (1.75x higher plasma levels vs standard PEA). Every clinical trial showing significant results used micronized or ultramicronized PEA.
After 6 to 8 weeks of consistent use, skip PEA for 3 days. If discomfort comes back within 48 to 72 hours, you have your answer from your own body, not from us. Most subscribe right after the pause test.
Loading phase (month 1): one bottle lasts ~30 days at 4 capsules/day. Maintenance (month 2+): one bottle lasts ~60 days at 2 capsules/day. The Buy 2 Get 1 Free bundle covers your full loading phase plus two months of maintenance.
Not recommended during pregnancy, nursing, or for anyone under 18. Consult your physician before use.
30-day money-back guarantee from the day your order is delivered. Email hello@blissta.co with your order number and we refund the product price within 24 hours. No return required, keep the bottle. No questions asked.
Chronic pain and migraines here. For the first time in 20 years, my pain level is below that of a broken bone. This stuff works!!!
Thanks for sharing your experience with us, Michael. We're glad to hear that you're finding support with our products. If you have any questions or need anything in the future, please feel free to reach out to us at hello@blissta.co.
Blissta Support
I had my doubts this would actually work. But after 2 weeks started noticing a difference. Back pain is not gone. And sciatica still acts up. But pain is significantly less. I am able to do more using them.
Hi Mark,
So glad to hear you're feeling a difference after two weeks. We appreciate you taking the time to share your feedback with us. If you ever have questions or need assistance, feel free to drop us a note at hello@blissta.co.
Blissta Support
Wonderful stuff. With stenosis in my lower back, and arthritis in both hips, I was taking diclofenac pills twice a day. With PainBloc, I am off diclofenac completely!
Thanks for sharing your experience with us, Lyle. We really appreciate the feedback. Just a quick note that nothing about this requires you to stop anything you are currently taking.
Blissta Support
These are amazing. I have had pain for decades and had many different painkillers including Tramadol and Gabapentin and none of them have had much affect on my pain. PEA has given me my life back by controlling the pain
Glad to hear you're having such a positive experience with PainBloc, Raelene. We appreciate you taking the time to share your feedback. If you have any questions in the future, feel free to email us at hello@blissta.co.
Blissta Support
Seems to have reduced my pain.
Thanks for taking the time to share your experience with the PainBloc, Donna. We're glad to hear you're having a positive experience.
Blissta Support
Since I began using the PEA, I have been able to stop taking Advil for my muscle and arthritic pain.
Hi Lawrence, thanks for sharing your experience with us. Nothing about this requires you to stop anything you are currently taking. We'd love to hear more about how you're doing, so feel free to reach out to us at hello@blissta.co anytime.
Excellent.
Thanks for sharing that, Al. We're glad to hear you're enjoying the PainBloc.
I use it for my neuropathy and even if I'm not taking it so long now, I feel relief.
Thanks so much for taking the time to share your feedback with us. We really appreciate you letting us know how the product is working for you. If you ever have any questions or need a hand with anything, feel free to reach out to our team at hello@blissta.co.
After eating the 1st dosage, i can immediately feel the relief of pain. But when the dosage subside ard the 20th hour, i can feel the pain again just like how i feel for the medical dosage of garbapentin. Hopefully after 1 bottle of dosage, the relief can last longer.
Thanks for sharing your experience with PainBloc. We're happy to hear your feedback, and if you have any questions or would like to chat further about your experience, please feel free to reach out to us directly at hello@blissta.co.
Works well.
Hi Josh! We're so glad to hear that the PEA is working well for you. We truly appreciate you taking the time to share your experience and thank you for choosing our product. We look forward to continuing to support your wellness journey!
